Sodium salicylate is a sodium salt of salicylic acid. It can be prepared from sodium phenolate and carbon dioxide under higher temperature and pressure. Historically, it has been synthesized by refluxing methyl salicylate (wintergreen oil) with an excess of sodium hydroxide.
| Item |
Sodium salicylate |
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Appearance |
White crystalline powder, soluble in water. It dissolves in dilute acid and alkaline solutions. |
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Identification |
a) TLC results |
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b) Color reaction with sulfuric acid |
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c) Color reaction with silver nitrate |
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Ph |
4.5 to 7.0 |
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Specific optical rotation |
-203°to -216°° |
Sodium salicylate is used in medicine as an analgesic and antipyretic.Sodium salicylate also acts as non-steroidal anti-inflammatory drug (NSAID), and induces apoptosis in cancer cells and also necrosis.It is also a potential replacement for aspirin for people sensitive to it. It may also be used as a phosphor for the detection of vacuum ultraviolet radiation and beta radiation.
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