Inositol hexaphosphate (IP6) is a naturally occurring polyphosphorylated carbohydrate that is present in substantial amounts in almost all plant and mammalian cells. It was recently recognized to possess multiple biological functions. A striking anticancer effect of IP6 was demonstrated in different experimental models. Inositol is also a natural constituent possessing moderate anticancer activity. The most consistent and best anticancer results were obtained from the combination of IP6 plus inositol. In addition to reducing cell proliferation, IP6 increases differentiation of malignant cells, often resulting in a reversion to normal phenotype. Exogenously administered IP6 is rapidly taken into the cells and dephosphorylated to lower-phosphate inositol phosphates, which further interfere with signal transduction pathways and cell cycle arrest. Enhanced immunity and antioxidant properties can also contribute to tumor cell destruction. However, the molecular mechanisms underlying this anticancer action are not fully understood. Because it is abundantly present in regular diet, efficiently absorbed from the gastrointestinal tract, and safe, IP6 holds great promise in our strategies for the prevention and treatment of cancer. IP6 plus inositol enhances the anticancer effect of conventional chemotherapy, controls cancer metastases, and improves the quality of life, as shown in a pilot clinical trial. The data strongly argue for the use of IP6 plus inositol in our strategies for cancer prevention and treatment. However, the effectiveness and safety of IP6 plus inositol at therapeutic doses needs to be determined in phase I and phase II clinical trials in humans.
Inositol hexaphosphate is a chemical found in beans, brown rice, corn, sesame seeds, wheat bran, and other high-fiber foods. It is converted into compounds in the body that are used by cells to relay outside messages to the cell nucleus. IP6 also aids the body in its use, or metabolism, of calcium and other minerals.
IP-6 is a very specific form of inositol, and there are several other forms of it found in the human body. It is different, for instance, from myo-inositol, which is another form being studied because of its possible role in illnesses such as depression and anxiety.
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| Synonyms |
IP6, IP-6, InsP-6, inositol, phytic acid, phytate, myo-inositol hexaphosphate, inositol-1,2,3,4,5,6-hexakisphosphate |
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| SPECIFICATION |
Item Specifications
Characteristics White to off-white odorless powder
Total Phosphorus ≥19.0%
CaMg Phytate content ≥85.0%
Identification Complies
Calcium ≥17.0%
Magnesium 0.5%--5.0%
Residue on ignition 68.0%--78.0%
Arsenic ≤3.0ppm
Lead ≤3.0ppm
Cadmium ≤1.0ppm
Mercury ≤0.1ppm
Heavy metal ≤10ppm
Loss on drying <10.0%
Total plate count ≤1,000cfu/g
Packing:25kg N.W.paper drum with double PE liner inside. (Diameter 380mm;Height 540mm),Or as order.
Storage:Store in cool, dry place,avoid heat and light. |
Hebei Huanwei Biotech Co.,Ltd was established in 2016 and located in Shijiazhuang, Hebei Province, China. Our advantage raw material products are widely used in pharmaceutical and food industry, such as Vitamins,Nutritional Ingredients, Food Additives,Dietary Supplements, Amino Acid, APIs and so on. Besides, we supply OEM/ODM products of Dietary-supplement, including Softgel, Tablet, Hard Capsule, Functional Beverage, Gummy and others.
Huanwei Biotech has obtained the certification of ISO9001, ISO14001, ISO45001 and have been awarded Ecovadis Bronze Medal in 2023. At present we have been supplying products and services to customers in more than 20 countries in Europe, North America, South America, Africa, Southeast Asia, etc.
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